论文标题

粘粒子颗粒的传输

Viscophoretic particle transport

论文作者

Khandan, Vahid, Boerkamp, Vincent, Jabermoradi, Abbas, Fontana, Mattia, Hohlbein, Johannes, Verpoorte, Elisabeth, Chiechi, Ryan C., Mathwig, Klaus

论文摘要

粘度是液体的基本特性,并确定悬浮颗粒的扩散率。粘度的梯度导致扩散率的梯度,但尚不清楚这种梯度是否会导致颗粒的定向运输。在这项工作中,我们使用高分辨率显微镜在微流体通道中生成陡峭,稳定的粘度梯度,并对产生的悬浮纳米颗粒在单粒子水平上运输。我们观察到高粘湿漂移速度显着超过理论预测。另外,我们利用粘膜粘膜进行新型的粒子陷阱。我们提供了对任何系统和表现出粘度梯度的任何应用的运输现象的首次量化,例如使用膜技术以及细胞间和细胞内生物分子转运的分离。

Viscosity is a fundamental property of liquids and determines the diffusivity of suspended particles. A gradient in viscosity leads to a gradient in diffusivity, yet it is unknown whether such a gradient can lead to directed transport of particles. In this work, we generate a steep, stable viscosity gradient in a microfluidic channel and image the resulting transport of suspended nanoparticles at the single-particle level using high-resolution microscopy. We observe high viscophoretic drift velocities that significantly exceed theoretical predictions. In addition, we utilize viscophoresis for a new type of particle trap. We provide a first quantification of a transport phenomenon that is of importance in any system and any application exhibiting viscosity gradients, for example in separation using membrane technology as well as in inter- and intracellular biomolecular transport.

扫码加入交流群

加入微信交流群

微信交流群二维码

扫码加入学术交流群,获取更多资源