论文标题

是什么使我们成为人类:人类和水果般的连接组的关键动态差异

What makes us humans: Differences in the critical dynamics underlying the human and fruit-fly connectome

论文作者

Ódor, Géza, Deco, Gustavo, Kelling, Jeffrey

论文摘要

先前对人连接组的模拟研究表明,临界动力学在所谓的格里菲斯阶段中出现。 %这是图形强异质性的结果。现在,我们使用Kuramoto同步模型在最大的最大可用大脑网络(21.662 $节点果-fly Connectome)上进行了研究。由于该图不那么异质,缺乏模块化结构并表现出较高的拓扑维度,因此我们期望与以前的结果有所不同。实际上,同步转变是平均场类似的,并且过渡区域的宽度比随机图中的宽度大,但比KKI-18人类连接组小得多。这证明了模块化结构和维度对动态的影响,为更好地理解人类的复杂批判动力学提供了基础。

Previous simulation studies on human connectomes suggested, that critical dynamics emerge subcrititcally in the so called Griffiths Phases. %This is the consequence of the strong heterogeneity of the graphs. Now we investigate this on the largest available brain network, the $21.662$ node fruit-fly connectome, using the Kuramoto synchronization model. As this graph is less heterogeneous, lacking modular structure and exhibit high topological dimension, we expect a difference from the previous results. Indeed, the synchronization transition is mean-field like, and the width of the transition region is larger than in random graphs, but much smaller than as for the KKI-18 human connectome. This demonstrates the effect of modular structure and dimension on the dynamics, providing a basis for better understanding the complex critical dynamics of humans.

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