论文标题

组织移植实验的推断

Inference on tissue transplantation experiments

论文作者

Wang, Yue, Zhang, Boyu, Kropp, Jérémie, Morozova, Nadya

论文摘要

我们回顾了有关各种物种组织移植实验的研究:切除一块供体组织并将其移植到宿主组织中的缝隙中,然后观察该移植组织的行为。尽管我们知道了一些移植实验的结果,但还有更多可能的实验,结果未知。我们开发了一种基于惩罚函数的方法,该方法使用已知的实验结果来推断未知的实验结果。没有类似结果的类似实验会受到惩罚,并对应较小的概率。该方法可以提供一组实验的最可能结果,也可以为每个实验提供特定结果的概率。该方法也被推广到其他情况。此外,我们解决了一个问题:如何设计实验,以便可以最有效地应用这种方法。

We review studies on tissue transplantation experiments for various species: one piece of the donor tissue is excised and transplanted into a slit in the host tissue, then observe the behavior of this grafted tissue. Although we have known the results of some transplantation experiments, there are many more possible experiments with unknown results. We develop a penalty function-based method that uses the known experimental results to infer the unknown experimental results. Similar experiments without similar results get penalized and correspond to smaller probability. This method can provide the most probable results of a group of experiments or the probability of a specific result for each experiment. This method is also generalized to other situations. Besides, we solve a problem: how to design experiments so that such a method can be applied most efficiently.

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